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Does Depression Run in Families? Genetic Factors Explained

Does Depression Run in Families? Genetic Factors Explained

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In examining the many factors that can contribute to depression, it's important to recognize the influence of family history.

Seeing a family member affected by depression can be concerning, and it's completely normal to wonder if you could experience or are experiencing the same. Genetics aren't the sole determinant, but they can play a role in our mental health.

However, when depression runs in your family, even if you don't experience it directly, you may find yourself coping with how to handle the symptoms of someone who does.

In this insightful guide, we'll explore what scientific research has to say about the genetic underpinnings of depression, how family history can influence mental health, what you can do to address the risk, and how to support family members with depression.

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What we know about heredity and depression

Depression is a complex mental health condition affected by many factors, including genetics, circumstances, environment, and choices.

We've long been aware that family history can be a significant predictor of depression, as related individuals can share both physical and psychological traits.

The question is, to what extent is depression dictated by our genes?

What the research says about genetic factors of depression 

Empirical evidence bolsters the idea that genetics have a hand in depression: 

  • There are higher rates of depression among identical twins compared to fraternal twins. 
  • Adopted individuals are at an increased risk of depression if their biological parents had a history of depressive disorders, regardless of whether they were raised by these parents or not.
  • The 5-HTT gene has variations known to be associated with an increased risk of depression when paired with specific life stressors.

Is a family history of depression a predictor?

The estimates for whether we inherit depression through genes vary, but they typically fall in the 30% to 40% range. So, while generics and depression can be linked, it's important to remember that your destiny isn’t solely written by your DNA.

An estimated 60% to 70% of people with depression have no family history of the condition. This means genetics, while influential, are just one piece of the puzzle.

The importance of other factors, such as early life experiences and one’s current environment, can’t be dismissed either. These circumstances can interact with genetic predispositions to influence the onset and severity of depression.

How family history influences depression risk

Understanding the role of heredity and depression risk can be empowering. Individuals may feel a shadow of inevitability from their family's mental health history, but awareness and proactive steps can buffer against this risk.

Recognize the importance of environmental factors

While a family's genetic makeup is significant, the environment can be equally powerful in shaping mental health outcomes. It's a classic case of nature versus nurture, where both sides play a part.

Stressful life events, childhood trauma, school or work issues, relationship troubles, financial strain, and chronic illness are all environmental factors that can trigger or intensify depression.

The first steps to reducing your risk of depression

If you have a family history of depression, you’ll want to adopt a lifestyle that prioritizes mental well-being. Even with a genetic predisposition, you increase your resilience against the development of the condition with these simple first steps:

  • Exercising regularly
  • Eating a balanced diet
  • Getting quality sleep
  • Implementing stress management techniques 

Therapy, particularly cognitive-behavioral therapy (CBT), and mindfulness-based practices have been shown to be effective for individuals at risk of depression. These practices can intervene upon the thought patterns and behaviors that contribute to depressive disorders, lessening their impact.

Test it out: To get started, you can try our free CBT thought record worksheet to better understand your emotions and mental well-being, or try our guide on the basics of mindfulness.

Adopting these strategies doesn't diminish the importance of seeking professional help if needed. Discussing your risk with a mental health provider can lead to a personalized plan for monitoring and addressing your mental health proactively.

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Managing depression when you have a family history

In many cases, the best course of action may be a combination of therapy and medication, such as antidepressants or mood stabilizers. Here’s what you can do if you think you might be experiencing depression.

Take preventative measures

If you’re an individual with a family history of depression, being proactive about mental health and taking preventative actions like the ones below can be crucial.

  • Build a support network.
  • Practice self-care as you can.
  • Set boundaries when you can.
  • Be open to professional advice and support.

Seek professional help

Depression can manifest itself gradually or hit you all at once after a major life event. For those with a family history, it's important to be aware of the signs of depression like the ones below and seek help early.

  • A change in sleep or appetite 
  • Persistent low mood
  • Difficulty concentrating
  • Feelings of hopelessness
  • Thoughts of self-harm 

Need immediate help?

  • Call 911 if you’re having a mental health emergency.
  • Text HOME to 741-741 if you're in emotional distress and need immediate support.
  • Call 988 for the National Suicide Prevention Hotline.

How to cope with depression in families

While genetic factors play a role in depression, they are far from the only elements at play. However, it doesn’t mean you’re not going to be without having to deal with depression’s symptoms.

To be perfectly honest, you may have to cope — or have been coping — with them in a second-hand fashion. And, just like in family matters, it isn’t something you should have to do alone.

You may not find that you have someone in your circle who understands what you’re dealing with, but we can assure you that our experienced mental health professionals do.

Having a licensed therapist that you can talk to about the issues or concerns you have related to a family member or loved one experiencing depression brings a level of professional understanding to the complex nature of depressive disorders. Additionally, they can offer expert guidance on how to effectively support that loved one while also addressing your own mental well-being and needs.

At Cerebral, we recognize the importance of holistic care, creating a supportive space for both those experiencing depression and their families, where empathy and understanding pave the way towards healing and growth. For that reason, our plans are on a flexible and convenient month-to-month subscription, where you can address your needs as they come up. 

Addressing a family history of depression

The interplay between genetics, environment, and personal experiences is what really shapes our mental health. Recognizing this complexity can empower you to take control and make a profound impact on your well-being, transcending your family history.

It's about understanding the cards you’ve been dealt, while also recognizing the many ways you can stack the deck in your favor.

Seeking out supportive resources, engaging in self-awareness, using multimodal strategies, and being proactive in managing your mental health can lead to a fulfilling and resilient life. 

Remember: you are not just your genetics; you have the ability to shape your life and your mental wellness.

We’re here to help

Discover what partnering with Cerebral looks like — no matter your needs — by exploring our approach to online therapy, medication management and developing personalized care plans.

If you feel like you may have symptoms of depression, you can also take our free emotional assessment when you sign up.

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You may be more likely to experience this if you have: A history of depression or bipolar disorder Negative feelings toward the pregnancy Hormonal changes Sleep deprivation A baby in neonatal intensive care (NICU) Low estrogen and progesterone levels after delivery Signs to watch for include these perinatal (postpartum) depression symptoms: Difficulty bonding with the baby Sadness Anxiety Changes in sleep or meal patterns Intense irritability and anger Early intervention is key to recovery, and recognizing and treating this type of depression promptly is critical to support both your and your baby’s well-being. Treatment and support options Perinatal (postpartum) depression is typically treated with medication, counseling, or a combination of the two. Working with a qualified care team is incredibly valuable, as they can consider your and your baby’s specific needs. Support from friends, family, and support groups can be essential in managing the symptoms as well as navigating a new development in life — whether it’s your first child or one of several. Situational depression Situational depression is an adjustment disorder with a depressed mood. This short-term condition occurs in response to a specific stressor or live event, such as an illness or death. It can also occur following a significant life adjustment, such as job change, move, or divorce, or be triggered by a challenging situation like a legal battle, difficult relationship, or tumultuous work environment. Situational depression vs. MDD Some symptoms of situational depression can be the same as those seen in other depressive disorders, including changes in mood and behavior and physical symptoms like headaches or stomach issues. While it may share some specific similarities with MDD, the depressed state typically ends once the situation is resolved or you adjust to the life change or event. In short, the biggest differentiating factor is that situational depression occurs after a specific event or stressor, whereas MDD can occur without any apparent trigger. Treatment and coping strategies With the support of friends, family, and/or a mental health professional, individuals can work through situational depression. It typically can’t be prevented, but healthy coping mechanisms, as well as self-care practices like exercise, proper nutrition, and mindfulness techniques, can help alleviate symptoms and promote overall well-being. Coping strategies for situational depression may also include problem-solving techniques, stress management, and therapy. In some cases, medication may be prescribed to alleviate symptoms. The importance of understanding the types While the symptoms of various depressive disorders may overlap, each type has its own distinct features and treatment considerations. The sooner individuals understand what type of depression they are dealing with, the faster they can work toward a game plan to manage their symptoms. If you're experiencing symptoms of depression, it's essential to seek help from a qualified mental health professional. Depressive disorders are treatable, and reaching out for support is a first step toward healing. Whether you're unsure about your symptoms or seeking guidance on next steps, our licensed therapists and prescribers are here to help. Cerebral’s mental health professionals can help you manage your symptoms and improve your quality of life by offering individualized treatment plans, online therapy sessions, and ongoing support. By educating yourself about the different types of depressive disorders and seeking personalized support, you can take control of your mental health. Am I depressed? Asking that question can be an initial step to finding answers and, more importantly, tailored support and interventions that address your unique needs. To learn more about the level of your depression symptoms, take our 3-minute depression screener today.  Images by freepik, freepik, freepik, freepik, and Drazen Zigic on Freepik. The information in this blog is provided as a general educational resource only, and is not to be used or relied on for any diagnostic or treatment purpose. This information should not be used as a substitute for professional diagnosis and treatment and does not create any patient-physician relationship between you and Cerebral. Please consult your health care provider before making any health care decisions or to get guidance about a specific medical condition.
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